Blue rubber bleb nevus syndrome brbns is a rare condition that is characterized by numerous malformations of the venous system that significantly involve the skin and visceral organs. See 600195 for a familial venous malformation syndrome vmcm that may be the same as the blue rubber bleb nevus syndrome of bean 1958 and is caused by mutation in the tek gene 600221. The underlying blood vessel malformations are present from birth even though the nevus may not be visible until later in life.
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